Ok. Just a quick warning. I've been doing more research. It appears that a "cleaner wax" in its simplest form and by definition is simply meant to clean the surface of contaminants before waxing. That alone should not affect the clear coat, since, in my opinion, that sounds like the intention of a claybar, which would be the preferred method of removing contaminants for wax. However, I've seen a few links on a Mercedes and BMW forum that shows the Meguiar Cleaner Wax as containing a slight abrasive. This, used excessively and over years of time, would diminish the clearcoat. So, I guess the actual response to your question, is sometimes. It would depend on the type of cleaner wax and the components of it.